高校招聘

英国牛津大学2022年招聘博士后（基因组稳定性）

牛津大学（university of oxford；勋衔：oxon或oxf），简称“牛津”（oxford），位于英国牛津，是一所公立研究型大学，采用传统学院制。是罗素大学集团成员，被誉为“金三角名校”和“g5”之一。牛津大学的具体建校时间已不可考，但有档案明确记载的最早的授课时间为1096年，之后在1167年因得到了英国王室的大力支持而快速发展。

postdoctoral researcher in genome stability

university of oxford

postdoctoral researcher in genome stability

department of oncology, old road campus research building, headington, oxford, ox3 7dq

this is a re-advertisement. previous applicants need not re-apply

about the role

applications are invited from enthusiastic, motivated individuals for a cruk- funded postdoctoral researcher position for professor madalena tarsounas's group, within the department of oncology. you will join an exciting research programme which combines cell/molecular biology and microscopy approaches with high-throughput technologies and bioinformatics to understand how brca1 and brca2 facilitate dna replication and how this, in turn, impacts chromosome segregation during mitosis. we have recently mapped genome-wide the sites where mitotic dna synthesis occurs in brca1/2-deficient cells (groelly et al. , molecular cell 2022; pmid: 36002001), using state-of-the-art technologies (e.g. midas-seq, high-content microscopy) and found that they co-localise with sites of r-loop formation. we now aim to investigate the roles of atr/atm kinases, as well as of mus81 (lai et al. nat. communications 2017) and other nucleases in regulating this process.

in this role, you will work as part of a team of postdoctoral researchers, collaborating with researchers from across the university of oxford's various technology platforms. you will be responsible for developing and testing your own hypotheses, generating high-quality and reproducible data, participate in dissemination activities and aid in manuscript preparation. you will also be required to provide guidance/supervision to other members of the research group, including phd/mres students.

the position is based in the department of oncology, old road campus research building, headington, oxford, ox3 7dq and is offered on a full-time, fixed- term basis for three years.

an early start date is required.

about you

you will hold (or be very close to completing) a dphil/phd in oncology, biology or other related discipline, together with relevant experience. experience in dna damage signalling and repair is essential, together with computer literacy and a good record of publication(s) in internationally recognised journals. experience with analysis of chip-seq and/or edu-seq data would be advantageous.

application process

applicants should read the job description before completing their application. you will be required to upload a supporting statement, setting out how you meet the selection criteria, a cv, including a statement of career interests, and the contact details of two referees as part of your online application.

informal enquiries can be directed to professor madalena tarsounas: madalena.tarsounas@oncology.ox.ac.uk

only applications received by 12pm gmt on friday 20 january 2023 will be considered.

committed to equality and valuing diversity

contact person : hr officer vacancy id : 162202 contact phone : closing date & time : 20-jan-2023 12:00 pay scale : standard grade 7 contact email : recruitment@oncology.ox.ac.uk salary (￡) : grade 7: ￡34,308 - ￡35,333 per annum (up to first two points on scale available)

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